Publications

Rabbit endocarditis model

Title, authors, reference

04/2012

Efficacy of ceftaroline fosamil in combination with the non-beta-lactam beta-lactamase inhibitor avibactam against ampC-producing Enterobacter cloacae: comparative study with doripenem in a rabbit experimental endocarditis model. C. Jacqueline, C. Bretonniere, V. Le Mabecque, C. Desessard, G. Amador, A.F. Miegeville, G. Williams, G. Potel, J. Caillon. ECCMID 2012. n° P 2065.


03/2012

The optimal aminoglycoside and its dosage for the treatment of severe Enterococcus faecalis infection. An experimental study in the rabbit endocarditis model. L. Dubé, J. Caillon, C. Jacqueline, D. Bugnon, G. Potel, N. Asseray. Eur J Clin Microbiol Infect Dis published 8 march 2012


04/2011

Diffusion of ofloxacin in the endocarditis vegetation assessed with synchrotron radiation UV fluorescence microspectroscopy. Batard E, Jamme F, Villette S, Jacqueline C, de la Cochetière MF, Caillon J, Réfrégiers M. PLoS One. 2011 Apr 29; 6 (4)


04/2011

Comparison of ceftaroline fosamil, daptomycin and tigecycline in an experimental rabbit endocarditis model caused by methicillin-susceptible, methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus. Jacqueline C, Amador G, Batard E, Le Mabecque V, Miègeville AF, Biek D, Caillon J, Potel G. J Antimicrob Chemother. 2011 Apr; 66 (4): 863-6


10/2010

Evaluation of the in vivo efficacy of intramuscularly administered ceftaroline fosamil, a novel cephalosporin, against a methicillin-resistant Staphylococcus aureus strain in a rabbit endocarditis model. Jacqueline C, Caillon J, Batard E, Le Mabecque V, Amador G, Ge Y, Biek D, Potel G. J Antimicrob Chemother. 2010 Oct; 65 (10): 2264-5


12/2009

In vivo activity of a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin, ceftaroline, against vancomycin-susceptible and -resistant Enterococcus faecalis strains in a rabbit endocarditis model: a comparative study with linezolid and vancomycin. Jacqueline C, Caillon J, Le Mabecque V, Miègeville AF, Ge Y, Biek D, Batard E, Potel G. Antimicrob Agents Chemother. 2009 Dec; 53 (12)


05/2009

In vivo impact of the MexAB-OprM efflux system on beta-lactam efficacy in an experimental model of Pseudomonas aeruginosa infection. Boutoille D, Jacqueline C, Le Mabecque V, Potel G, Caillon J. Int J Antimicrob Agents. 2009 May; 33 (5): 417-20


02/2008

Efficacy of quinupristin/dalfopristin versus vancomycin, alone or in combination with rifampicin, against methicillin-resistant Staphylococcus aureus in a rabbit arthritis model. Hamel A, Caillon J, Jacqueline C, Batard E, Potel G. Int J Antimicrob Agents. 2008 Feb; 31(2): 158-60.


09/2007

In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model. Jacqueline C, Caillon J, Le Mabecque V, Miègeville AF, Hamel A, Bugnon D, Ge JY, Potel G. Antimicrob Agents Chemother. 2007 Sep; 51 (9): 3397-400.


01/2005

In vitro and in vivo synergistic activities of linezolid combined with subinhibitory concentrations of imipenem against methicillin-resistant Staphylococcus aureus. Jacqueline C, Navas D, Batard E, Miegeville AF, Le Mabecque V, Kergueris MF, Bugnon D, Potel G, Caillon J. Antimicrob Agents Chemother. 2005 Jan; 49 (1): 45-51.


10/2004

Comparison of in vivo intrinsic activity of cefepime and imipenem in a Pseudomonas aeruginosa rabbit endocarditis model: effect of combination with tobramycin simulating human serum pharmacokinetics. Navas D, Caillon J, Gras-Le Guen C, Jacqueline C, Kergueris MF, Bugnon D, Potel G. J Antimicrob Chemother. 2004 Oct; 54 (4): 767-71.


10/2004

In vivo efficacy of linezolid in combination with gentamicin for the treatment of experimental endocarditis due to methicillin-resistant Staphylococcus aureus. Jacqueline C, Asseray N, Batard E, Le Mabecque V, Kergueris MF, Dube L, Bugnon D, Potel G, Caillon J. Int J Antimicrob Agents. 2004 Oct; 24 (4): 393-6.


11/2003

Simulation of human gentamicin pharmacokinetics in an experimental Enterococcus faecalis endocarditis model. Dubé L, Caillon J, Gras-Le Guen C, Jacqueline C, Kergueris MF, Granry JC, Potel G, Bugnon D. Antimicrob Agents Chemother. 2003 Nov; 47 (11): 3663-6.


12/2002

In vivo efficacy of continuous infusion versus intermittent dosing of linezolid compared to vancomycin in a methicillin-resistant Staphylococcus aureus rabbit endocarditis model. Jacqueline C, Batard E, Perez L, Boutoille D, Hamel A, Caillon J, Kergueris MF, Potel G, Bugnon D. Antimicrob Agents Chemother. 2002 Dec; 46 (12): 3706-11.


10/2002

In vivo activity of amoxicillin in a non-toxigenic Corynebacterium diphtheriae rabbit endocarditis experimental model. Grandière-Perez L, Jacqueline C, Le Mabecque V, Patey O, Potel G, Bugnon D, Caillon J. Pathol Biol (Paris). 2002 Nov; 50 (9): 513-5.


07/2002

Combination of quinupristin-dalfopristin and gentamicin against methicillin-resistant Staphylococcus aureus: experimental rabbit endocarditis study. Batard E, Jacqueline C, Boutoille D, Hamel A, Drugeon HB, Asseray N, Leclercq R, Caillon J, Potel G, Bugnon D. Antimicrob Agents Chemother. 2002 Jul; 46 (7): 2174-8.


05/2002

Different aminoglycoside-resistant phenotypes in a rabbit Staphylococcus aureus endocarditis infection model. Asseray N, Caillon J, Roux N, Jacqueline C, Bismuth R, Kergueris MF, Potel G, Bugnon D. Antimicrob Agents Chemother. 2002 May; 46 (5): 1591-3.